Great Responsibility.
This is one of those things everyone knows deep down in their heart, without ever thinking about it much. Somehow, the guy (or girl) who has the ooommppff to wear a moustache also is a person not to be messed with.
In Family Guy (the Moustache episode called “McStroke”) season 6 episode 8, and is thought to be a reference to Spider Man. Peter mentions “With great mustache, comes great responsibility!” A spoof from Spider-man’s famous line; “With great power, comes great responsibility!”
Here’s a clip.